CLINICAL TRIALS UNDERWAY (AS OF 5/98)
WITH ANTI-ANGIOGENIC DRUGS
NOTE: This listing does not imply an endorsement
by us of clinical trials for cancer patients. But some people do wish to
participate in such trials, and so we are providing this list as a public
service. For more information on these trials speak to your oncologist
or call the National Cancer Institute at 1-800-4-CANCER. For information
on The Moss Reports call 718-636-4433.
1. Phase I Study of Carboxyamidotriazole Modulated by Ketoconazole in
Patients with Advanced Malignancies
2. Phase II Study of CAI in Patients with Refractory or Recurrent Ovarian
Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
3. Phase II Randomized Study of Oral Thalidomide in Hormone-Refractory
Adenocarcinoma of the Prostate
4. Phase II Study of Oral Carboxyamidotriazole in Patients with Androgren-Independent
Prostate Cancer
5. Phase II Study of Suramin for Metastatic Melanoma
6. Phase II Randomized Study of Oral Thalidomide in Metastatic Breast
Cancer
7. Phase II Study of Oral Thalidomide in HIV-Associated Kaposi's Sarcoma
8. Phase I Study of Oral COL-3 in Patients with Refractory Metastatic
Solid Tumors or Lymphoma
9. Phase II Pilot Study of Suramin for Refractory or Relapsed Multiple
Myeloma and Castleman's Disease
10. Phase I/II Pilot Study of Interleukin-12 for AIDS-Associated Kaposi's
Sarcoma
11. Phase II Study of Suramin for Recurrent Primary Adult Brain Tumors
12. Phase II Study of Suramin in Advanced Nonsmall Cell Lung Cancer
13. Phase II Study of TNP-470 for Advanced or Recurrent Squamous Cell
Carcinoma of the Cervix
14. Phase III Randomized Study of Marimastat versus Placebo in Patients
with Metastatic Breast Cancer Who Have Responding or Stable Disease After
Induction Chemotherapy
15. Phase II Study of Suramin for Recurrent or Progressive Malignant
Glioma
16. Phase I Study of Carboxyamidotriazole plus Paclitaxel for Advanced
Solid Tumors and Refractory Lymphomas
17. Phase III Randomized Study of TNP-470 vs Synchronous Radiotherapy
and 5-FU/CF for Locally Advanced Nonresectable Nonmetastatic Pancreatic
Cancer
18. Phase I Study of Carboxyamidotriazole for Refractory Cancers
19. Phase I Study of TNP-470 in Patients with Recurrent or Refractory
Pediatric Solid Tumors, Lymphomas, and Acute Leukemias
20. Phase III Randomized Study of Marimastat in Patients with Small Cell
Lung Cancer following a Response to First Line Chemotherapy