From The Cancer Chronicles #29
© Sept. 1995 by Ralph W. Moss, Ph.D.

The relationship between a key hormone of pregnancy, human chorionic gonadotropin (HCG), and human cancer received a powerful boost in May when NCI's celebrated researcher Robert Gallo claimed that the hormone could be used as a treatment to fight Kaposi's sarcoma (KS), a type of cancer common in men with AIDS. "Tumorigenesis and metastasis of [a] neoplastic Kaposi¹s sarcoma cell line in immunodeficient mice [is] blocked by a human chorionic gonadotropin (hCG), a pregnancy hormone," Gallo, co-discoverer of the HIV virus, wrote in the May 4, 1995 Nature. Gallo¹s coworkers, Philippe Hermans (Brussels) and Jacques Besnier (Paris) said that they had discovered that HCG participates in the hormonal regulation of new blood vessel formation. They speculate that it is the presence of this hormone at various points in their lives that keeps women from often developing Kaposi¹s sarcoma, a kind of skin malignancy. Dr. Hermans related the story of an African woman who had an AIDS-related Kaposi¹s sarcoma, with 14 growing lesions. But after she became pregnant all these tumors stopped growing. And less than a year later, the tumors had completely disappeared and her baby was also free of the dreaded KS. Similarly, a 27-year-old Caucasian women who had had five KS tumors disappear within the first two months of her pregnancy. Gallo claimed that in the test tube HCG killed the AIDS-related Kaposi cells that caused malignant tumors. In another experiment, all the nude mice (which, because of defective immune systems, lack a natural resistance to cancer) injected with KS cells developed cancer, except for those that became pregnant. These pregnant animals remained tumor-free. Female animals injected with cancer cells during the first ten days of their pregnancy (when the hormone is highly active) also failed to develop cancer. "To our knowledge, this is the first demonstration of an anti-tumor property of beta human chorionic gonadotropin," wrote Gallo and his co-authors. This should raise a few smiles among readers of this newsletter, who read about the link between HCG and cancer in past issues. HCG is produced by the so-called trophoblastic cell of pregnancy, a cell that is responsible for the adhesion of the life-giving placenta to the mother's uterine wall. The link between trophoblast and cancer dates back to the summer of 1902, when a University of Edinburgh lecturer in embryology named John Beard published the first of his epochal observations in the Lancet on the many points of identity between trophoblast and cancer. These were later collected into a 1911 book called "The Enzyme Treatment of Cancer," which was popular in its day, but has since gone out of print. The link is central to the work of Ernst T. Krebs, Jr., the controversial codiscoverer of Laetrile and founder of the John Beard Memorial Foundation. Krebs has maintained for over 40 years that cancer is in fact trophoblast in the wrong place at the wrong time ("in temporal and spatial anomoly," is how he usually phrases it.) The connection also forms the basis of the immuno-embryonal therapy of Valentin Govallo, MD of Moscow, which features the injection into cancer patients of a preparation of placental tissue, which is rich in HCG. The link between trophoblast and cancer has been brilliantly put forward by Rigdon Lentz, MD, who (without knowing Beard¹s work) published an article on the trophoblast-cancer link in a medical journal a decade ago. And since early this year, there have been clinical trials underway at several East Coast medical centers using a patented combination of HCG and another substance to fight cancer and cancer pain. In the past, Dr. Gallo erroneously laid claim to the sole discovery of the human immunodeficiency virus. This created an international scandal. Now NCI¹s most famous researcher is raiding the fertile fields of alternative medicine. Will anyone complain?

Ralph W. Moss, Ph.D. is director of the The Moss Reports for cancer patients. Dr. Moss is the author of eleven books and three documentaries on cancer-related topics. He is or has been an advisor on alternative cancer treatments to the National Institutes of Health, the National Cancer Institute, the American Urological Association, Columbia University, the University of Texas, the Susan G. Komen Foundation and the German Society of Oncology. He wrote the first article on alternative medicine for the Encyclopedia Britannica yearbook. He is listed in Marquis Who's Who in America, Who's Who in the World, Who's Who in the East, and Who's Who in Entertainment (as a film documentarian). This Web site does not advocate any particular treatment for cancer. We urge you to always seek competent medical advice for all health problems, especially cancer. Before consulting our site please read our full Disclaimer statement.

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