The big pharmaceutical companies, or so-called 'majors,' continue to gobble up their once-independent biotechnology rivals. The failure of Centocor, Inc. to get FDA approval for its new antibiotic, Centoxin, after a $450 million investment, sent shock waves throughout the industry.
"Centocor reminded people of the chokehold the FDA has on the industry, how difÞcult it is to go it alone," a biotech official told the Washington Post.
In recent months:
"The problem is not all of these strategic alliances work out, and if you ever want to get out of these alliances, it¹s difÞcult to get rid of the board members," one executive told the Washington Post.
But resistance grows: on October 26, Rep. Ron Wyden (D-OR) assailed Bristol-Myers Squibb for planning to charge too much for the new drug taxol. The company wants to sell the PaciÞc yew-derived cytotoxic drug for $680 per month, 3 to 6 times more than it should cost, the Congressman said in a letter to the head of the National Cancer Institute (NCI).
Bristol-Myers Squibb said it was premature to discuss pricing. But Wyden claims documents show that the company and NCI have decided the price should mirror Cisplatin, selling for $680 per month.
Last year, NCI gave Bristol-Myers semi-exclusive rights to use taxol experimentally. The deal requires B-M to pay only for the cost of managing the yew harvests. In return, they got a near-monopoly over this natural but toxic product.